virginiatech
 


Chang Lu, Associate Professor
Department of Chemical Engineering,
Virginia Tech-Wake Forest University School of Biomedical Engineering and Sciences
Virginia Tech
Blacksburg, VA 24061
 

 


Microfluidics, Single Cell Analysis, Gene Delivery, and Tissue Engineering

 

Lu Group 2011  
(From left to right): Chang Lu, Chen Sun, Bo Xiong, Yousef Awwad, Hamid Hassanisaber, Tao Geng, Ning Bao, Yihong Zhan, Zhenning Cao, Fangyuan Chen, and Nelie Loufakis (June 2011).  

Our research is concerned with the new science and technology generated by applying micro/nanofabricated structures and devices to biological studies and biosensors. One emphasis in our research is to develop high-throughput microfluidic tools to manipulate and analyze single cells and extract biological information. We have developed/invented microfluidic chemical cytometry, Coherent anti-stokes Raman scattering (CARS) flow cytometry, electroporative flow cytometry, total internal reflection fluorescence (TIRF) flow cytometry over recent years for a variety of applications. Another thrust in the group is on developing flow-through electroporation for efficient gene delivery into cells. Our ultimate goal is to apply this technique to create genetically modified cells for cancer immunotherapy, stem cell therapy and tissue regeneration. We also work on conducting cellular assays based on genetic/epigenetic and proteomic analysis. Finally, we are interested in developing various biosensors for different applications.


Announcements

  • We welcome inquiries about openings for postdoc, graduate and undergraduate researchers. Interested individuals are encouraged to contact Dr. Lu.

   
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